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Wild Mushrooms

About Psilocybin

Psilocybin has gained increasing attention in recent years as research demonstrates its potential to support mental health and emotional well-being. Clinical studies show that psilocybin, when used in safe and supportive settings, can reduce symptoms of depression, anxiety, and existential distress. For example, studies with palliative care patients have found that many individuals were open to psilocybin-assisted therapy, particularly because of its ability to relieve stress and anxiety tied to end-of-life concerns. Other trials highlight psilocybin’s unique capacity to help individuals reconnect with meaning and purpose, a benefit that traditional medications often fail to address.

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Beyond palliative care, psilocybin is showing promise in broader psychiatric treatment. Recent pilot studies have paired psilocybin with cognitive behavioral therapy for major depressive disorder, finding improvements in depressive symptoms and enhanced resilience against relapse. Research also shows encouraging outcomes in treatment-resistant depression and even in certain cases of bipolar II disorder. Clinical trials and therapeutic models are also exploring psilocybin as a tool for healing post-traumatic stress disorder (PTSD). By promoting neuroplasticity, calming overactive fear responses, and supporting the deep processing of traumatic memories, psilocybin can help veterans, first responders, and trauma survivors work through the root causes of PTSD in ways that traditional approaches often cannot.

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Another promising area of research is in addiction recovery. Psilocybin has been studied as an aid in overcoming dependence on substances such as alcohol, nicotine, and opioids. The medicine appears to work by disrupting ingrained patterns of thought and behavior while opening space for new perspectives, emotional breakthroughs, and a sense of connection that supports long-term recovery. When combined with therapy, psilocybin may help individuals break cycles of craving and relapse by fostering resilience, self-compassion, and clarity of purpose. For many, it creates a powerful opportunity to reset their relationship with themselves and begin a healthier path forward.

 

On this website, you’ll find a curated library of scientific studies, dosing protocols, and clinical insights that outline both the promise and precautions of psilocybin-assisted therapy. These resources include detailed charts on safe dosing, peer-reviewed articles on therapeutic applications, and case studies that document real-world benefits. We encourage you to explore the research for yourself, so you can make an informed decision about how psilocybin may support healing, resilience, and personal growth. By grounding curiosity in evidence, individuals can approach this powerful medicine with both hope and respect.

Studies and Resources

STUDY:
Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later

STUDY:
Psilocybin for Opioid Use Disorder in Two Adults Stabilized on Buprenorphine: A Technical Report on Study Modifications and Preliminary Findings

RESEARCH ARTICLE:
Psilocybin-Assisted Cognitive Behavioral Therapy for Adults with Major Depressive Disorder: Rationale and Treatment Development

STUDY:
Impact of Psilocybin on Peripheral Cytokine Production

STUDY:
Psychedelic-Assisted Therapy Training: An Argument in Support of Firsthand Experience of Nonordinary States of Consciousness in the Development of Competence

RESEARCH ARTICLE:
Psychedelic Use Among Psychiatric Medication Prescribers: Effects on Well-Being, Depression, Anxiety, and Associations with Patterns of Use, Reported Harms, and Transformative Mental States

STUDY:
Psilocybin-Assisted Therapy May Enhance Conservation Values in Patients with Alcohol Use Disorder

STUDY:
A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression

STUDY:

Therapeutic effects of Low-Dose Psilocybin in Depression and other mental Disorders

RESEARCH ARTICLE:
Psilocybin-Assisted Psychotherapy for Treatment-Resistance Depression in Bipolar II Disorder

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